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KMID : 0931320180180020082
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대한상부위장관.헬리코박터학회지
2018 Volume.18 No. 2 p.82 ~ p.88
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Antimicrobial Resistance of Helicobacter pylori Isolates in Korea
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Gong Eun-Jeong
Ahn Ji-Yong
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Abstract
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Antimicrobial resistance is a growing problem in the eradication of Helicobacter pylori. A combination therapy with proton pump inhibitor, clarithromycin, and amoxicillin is recommended as the first-line treatment regimen in Korea. However, the eradication rate with a standard triple therapy has been unsatisfactory in the last decade, and one of the main reasons for treatment failure is the increasing prevalence of strains resistant to antimicrobials. Therefore, comprehensive and detailed information on antimicrobial resistance is mandatory to optimize the strategy of eradication treatment. The antimicrobial resistance of H. pylori is reported to vary according to study population, geographical region, and test methods. In this review, the prevalence of antimicrobial resistance of H. pylori isolates in Korea is summarized on the basis of recent studies.
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KEYWORD
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Antimicrobial drug resistance, Helicobacter pylori, Korea
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